Several medications are now recommended as first-line choices for treating gonorrhea of the genital and anal areas. A person who is diagnosed with gonorrhea is usually treated for NGU and chlamydia as well, because the likelihood of co-infection with the bacteria that cause these infections is high. Some gonorrhea treatments are given as an injection, some are available as a week-long course of oral medication, and some are available as a single pill—which is the easiest way to treat any infection.

A shot of ceftriaxone or a single dose of such oral medications as ofloxacin, cefixime, and ciprofloxacin will treat gonorrhea. Recently some gonorrheal resistance to ofloxacin has been reported in certain areas of the country. Other treatments are available if these are not well tolerated.

If more extensive infection—such as epididymitis, prostatitis, or PID—is suspected, then a longer course of antibiotics is necessary (see the sections on epididymitis and prostatitis and on pelvic inflammatory disease). For gonorrhea of the throat, either ceftriaxone or ciprofloxacin is usually given, since these antibiotics are more effective than the other choices. Talk with your health care provider about which treatment is best for you.


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